Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.400 None 0.916 190 7 1992 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.400 None 0.947 150 4 1999 2020
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.500 None 0.918 122 15 1996 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 0.936 110 4 2001 2020
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.200 None 0.900 110 7 1991 2020
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.500 None 0.989 89 16 1986 2020
Entrez Id: 4023
Gene Symbol: LPL
LPL
P06858 lipoprotein lipase Enzyme 290 0.474 0.808 1.3E-09 0.200 None 0.918 85 12 1993 2020
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 257 0.482 0.808 2.7E-17 0.500 None 0.987 76 3 2006 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 0.917 72 4 2001 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.100 None 1.000 43 4 2002 2020
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.400 None 0.833 36 1 2001 2020
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
P30556 angiotensin II receptor type 1 G-protein coupled receptor 440 0.423 0.846 5.3E-04 0.100 None 0.829 35 5 1996 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 0.906 32 1 2001 2020
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.100 None 1.000 31 0 1998 2020
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12
Q9H244 purinergic receptor P2Y12 G-protein coupled receptor 153 0.533 0.731 1.7E-03 0.100 None 1.000 26 0 2005 2020
Entrez Id: 3240
Gene Symbol: HP
HP
P00738 haptoglobin Enzyme 464 0.412 0.885 1.7E-05 0.100 None 0.960 25 0 1993 2020
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
P08254 matrix metallopeptidase 3 Enzyme 473 0.408 0.885 5.7E-15 0.400 None 0.957 23 2 1996 2020
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.100 None 0.947 19 1 2001 2020
Entrez Id: 4351
Gene Symbol: MPI
MPI
P34949 mannose phosphate isomerase Enzyme 101 0.585 0.654 1.2E-07 0.100 None 1.000 15 0 2017 2020
Entrez Id: 6943
Gene Symbol: TCF21
TCF21
O43680 transcription factor 21 143 0.537 0.692 0.83 0.500 None 0.933 15 2 2011 2020
Entrez Id: 406913
Gene Symbol: MIR126
MIR126
microRNA 126 305 0.447 0.846 0.100 None 1.000 10 0 2010 2020
Entrez Id: 260431
Gene Symbol: COPD
COPD
Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.080 None 1.000 8 0 2017 2020
Entrez Id: 7391
Gene Symbol: USF1
USF1
P22415 upstream transcription factor 1 82 0.592 0.692 2.4E-02 0.080 None 1.000 8 4 2007 2020
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.070 None 1.000 7 0 2015 2020
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.060 None 0.833 6 2 1988 2020